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Colorado vs. USC 2012: TV schedule, game time, spread and more

Matt Barkley and Co. are expected to cruise to victory over a team that struggles to stop people from scoring a lot of points against them.

Kirby Lee-US PRESSWIRE

The USC Trojans will host the Colorado Buffaloes on Saturday at 6:00 pm ET on the Pac-12 Network. It'll be the Trojans fifth Pac-12 game of the season.

The Trojans are coming off their third straight victory, this time over the Washington Huskies in Washington, 24-14. The Trojans are in first place in the Pac-12 South and haven't lost a game since Sept. 15 at Stanford.

The Buffaloes aren't having as great of a season. Colorado is 1-5 including a 1-2 record in the Pac-12 and are coming off two straight losses to UCLA and Arizona State by a combined score of 93-31. This game against the Trojans begins the gauntlet portion of the Buffaloes schedule as they travel to USC this week, to No. 3 Oregon next week and end it with a visit from No. 20 Stanford on Nov. 3.

The Buffaloes give up a whopping 41.3 points per game and the Trojans have reached the 41+ point plateau twice already this season.

The Trojans opened as 40-point favorites over the Buffaloes.