The senior captain apologized both in private in USC's locker room and publicly on Twitter.
"Sorry for giving everyone that scare early on! Gotta love this team for hanging tough, especially in that environment! #FightOn," Holmes tweeted after the 38-28 win.
Holmes, who has started at USC for three years, is a candidate for Rimington Trophy, which goes to the best center in the country, this season. The two bad snaps were uncharacteristic based on his body of work as a starter.
"I was not angry at Khaled,'' Barkley told the Daily News. "He's my best friend.''
Here is Holmes' first bad snap, which came on the very first play of the game.