Bryant, 34, leads the league in scoring at 29.2 points per game. He is also averaging 4.8 assists and five rebounds per game while shooting 48.8 percent from the floor.
With 639,419 votes, the Los Angeles Lakers guard has a large cushion over Los Angeles Clippers guard Chris Paul, who at 353,603 votes is second in the Western Conference among backcourt players. Houston point guard Jeremy Lin is third with 298,319 votes, Rockets teammate James Harden is fourth with 196,108 votes, and Oklahoma City's Russell Westbrook rounds out the top-five.
Bryant's teammate, Steve Nash, is in sixth place with 118,073 votes despite playing in only two games this year for the 9-13 Lakers.
In the frontcourt, Los Angeles Center Dwight Howard has 434,168 votes and trails only Kevin Durant, who is second to Bryant in the Western Conference with 605,965 votes. The Clippers' Blake Griffin is third in frontcourt voting and the San Antonio Spurs' Tim Duncan is fourth. Fellow Laker Pau Gasol is fifth among Western Conference frontcourt players with 139,868 votes while Metta World Peace has 59,167 votes.
Ballots for the 2013 All-Star game close on Jan. 14.